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HomeHealthA new gut–brain therapeutic target for hepatic encephalopathy

A new gut–brain therapeutic target for hepatic encephalopathy

Nature Medicine, Published online: 07 February 2025; doi:10.1038/s41591-024-03467-9

New evidence suggests that Ruminococcus gnavus in the gut induces monoamine synthesis and neurotoxicity in some patients with cirrhosis, causing hepatic encephalopathy — revealing a possible therapeutic target or predictive biomarker for this understudied condition.

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