Nature Medicine, Published online: 22 November 2024; doi:10.1038/s41591-024-03402-y
Metastatic spread of cancer to the brain has a devastating effect on patient outcomes, yet identifying patients who will develop brain metastases is difficult in current clinical practice. We show that DNA methylation signatures from lung adenocarcinomas can accurately predict which patients are at risk of metastasis to the brain, which could transform future cancer care.
