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HomeHealthA consensus immune dysregulation framework for sepsis and critical illnesses

A consensus immune dysregulation framework for sepsis and critical illnesses

Nature Medicine, Published online: 30 September 2025; doi:10.1038/s41591-025-03956-5

In an integrated analysis of transcriptomic data from the SUBSPACE consortium and public datasets of patients with sepsis, acute respiratory distress syndrome, trauma and burns, dysregulation within four consensus molecular clusters related to myeloid and lymphoid cells is associated with mortality and illness severity.

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