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HomeHealthCerebrospinal fluid biomarker predicts dementia onset and progression in Alzheimer’s disease

Cerebrospinal fluid biomarker predicts dementia onset and progression in Alzheimer’s disease

Nature Medicine, Published online: 28 April 2025; doi:10.1038/s41591-025-03700-z

Proteomics analyses of thousands of proteins in human cerebrospinal fluid reveal that the ratio of two proteins can be used to predict future dementia or cognitive resilience among people with Alzheimer’s disease brain pathology.

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