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HomeHealthImpact of the indigenous rotavirus vaccine Rotavac in the Universal Immunization Program in India during 2016–2020

Impact of the indigenous rotavirus vaccine Rotavac in the Universal Immunization Program in India during 2016–2020

Nature Medicine, Published online: 07 October 2025; doi:10.1038/s41591-025-03998-9

In this multicentered observational study, Rotavac, an indigenous, monovalent, live, attenuated, oral rotavirus vaccine, had an adjusted vaccine efficacy of 54% and protected against severe gastroenteritis in Indian children during its rollout between 2016 and 2020.

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